Pharmacological studies of anticancer, anti inflammatory activities of Murraya koenigii (Linn) Spreng in experimental animals

The aim of the present study is to evaluate the effect of column (SU I, SU II, SU III) extracts of the plant Murraya koenigi against in vitro (short term incubation method, SU I, SU II, SU III) and in vivo (Dalton’s Ascitic Lymphoma, SU II) has been evaluated in male swiss albino mice. DAL cells were injected intraperitoneally (10 cells) to the mice. Two days after cells injection the animals were treated with 7 mg/Kg of SU II for 15 days. 5-flurouracil (20 mg/Kg) was used as the reference. On day 16, cancer cell number compared with the same parameter in control. A significant decrease in the cancer cell number and tumour weight were noted in the tumour-induced mice after treatment with SU II. These observations are suggestive of the protective effect of extract in Dalton’s Ascitic Lymphoma (DAL). In vitro studies all the column extracts showed moderate activity.